Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft-like progenitor for pulmonary neuroendocrine ce...

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Autores principales:	Katherine C. Goldfarbmuren, Nathan D. Jackson, Satria P. Sajuthi, Nathan Dyjack, Katie S. Li, Cydney L. Rios, Elizabeth G. Plender, Michael T. Montgomery, Jamie L. Everman, Preston E. Bratcher, Eszter K. Vladar, Max A. Seibold
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9bcec16a7aeb4036b62487f931077a83
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spelling	oai:doaj.org-article:9bcec16a7aeb4036b62487f931077a832021-12-02T16:51:13ZDissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium10.1038/s41467-020-16239-z2041-1723https://doaj.org/article/9bcec16a7aeb4036b62487f931077a832020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16239-zhttps://doaj.org/toc/2041-1723Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft-like progenitor for pulmonary neuroendocrine cells and ionocytes.Katherine C. GoldfarbmurenNathan D. JacksonSatria P. SajuthiNathan DyjackKatie S. LiCydney L. RiosElizabeth G. PlenderMichael T. MontgomeryJamie L. EvermanPreston E. BratcherEszter K. VladarMax A. SeiboldNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katherine C. Goldfarbmuren Nathan D. Jackson Satria P. Sajuthi Nathan Dyjack Katie S. Li Cydney L. Rios Elizabeth G. Plender Michael T. Montgomery Jamie L. Everman Preston E. Bratcher Eszter K. Vladar Max A. Seibold Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
description	Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft-like progenitor for pulmonary neuroendocrine cells and ionocytes.
format	article
author	Katherine C. Goldfarbmuren Nathan D. Jackson Satria P. Sajuthi Nathan Dyjack Katie S. Li Cydney L. Rios Elizabeth G. Plender Michael T. Montgomery Jamie L. Everman Preston E. Bratcher Eszter K. Vladar Max A. Seibold
author_facet	Katherine C. Goldfarbmuren Nathan D. Jackson Satria P. Sajuthi Nathan Dyjack Katie S. Li Cydney L. Rios Elizabeth G. Plender Michael T. Montgomery Jamie L. Everman Preston E. Bratcher Eszter K. Vladar Max A. Seibold
author_sort	Katherine C. Goldfarbmuren
title	Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
title_short	Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
title_full	Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
title_fullStr	Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
title_full_unstemmed	Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
title_sort	dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/9bcec16a7aeb4036b62487f931077a83
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Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

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