Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft-like progenitor for pulmonary neuroendocrine ce...
Guardado en:
Autores principales: | Katherine C. Goldfarbmuren, Nathan D. Jackson, Satria P. Sajuthi, Nathan Dyjack, Katie S. Li, Cydney L. Rios, Elizabeth G. Plender, Michael T. Montgomery, Jamie L. Everman, Preston E. Bratcher, Eszter K. Vladar, Max A. Seibold |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9bcec16a7aeb4036b62487f931077a83 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Smoking shifts human small airway epithelium club cells toward a lesser differentiated population
por: Mahboubeh R. Rostami, et al.
Publicado: (2021) -
Taste Receptors: The Gatekeepers of the Airway Epithelium
por: Katleen Martens, et al.
Publicado: (2021) -
Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure
por: Heidi J. Nick, et al.
Publicado: (2021) -
The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.
por: Max A Seibold, et al.
Publicado: (2013) -
Somatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium
por: Nadzeya Marozkina, et al.
Publicado: (2021)