Generalized and scalable trajectory inference in single-cell omics data with VIA

Scalable trajectory inference for multi-omic single cell datasets is challenging in terms of capturing non-tree complex topologies. Here the authors present a method, VIA, that scales to millions of cells across multiple omic modalities using lazy-teleporting random walks.

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Autores principales:	Shobana V. Stassen, Gwinky G. K. Yip, Kenneth K. Y. Wong, Joshua W. K. Ho, Kevin K. Tsia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9bd006f35d39495d922c8c86b7b6b9a2
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spelling	oai:doaj.org-article:9bd006f35d39495d922c8c86b7b6b9a22021-12-02T15:15:14ZGeneralized and scalable trajectory inference in single-cell omics data with VIA10.1038/s41467-021-25773-32041-1723https://doaj.org/article/9bd006f35d39495d922c8c86b7b6b9a22021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25773-3https://doaj.org/toc/2041-1723Scalable trajectory inference for multi-omic single cell datasets is challenging in terms of capturing non-tree complex topologies. Here the authors present a method, VIA, that scales to millions of cells across multiple omic modalities using lazy-teleporting random walks.Shobana V. StassenGwinky G. K. YipKenneth K. Y. WongJoshua W. K. HoKevin K. TsiaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shobana V. Stassen Gwinky G. K. Yip Kenneth K. Y. Wong Joshua W. K. Ho Kevin K. Tsia Generalized and scalable trajectory inference in single-cell omics data with VIA
description	Scalable trajectory inference for multi-omic single cell datasets is challenging in terms of capturing non-tree complex topologies. Here the authors present a method, VIA, that scales to millions of cells across multiple omic modalities using lazy-teleporting random walks.
format	article
author	Shobana V. Stassen Gwinky G. K. Yip Kenneth K. Y. Wong Joshua W. K. Ho Kevin K. Tsia
author_facet	Shobana V. Stassen Gwinky G. K. Yip Kenneth K. Y. Wong Joshua W. K. Ho Kevin K. Tsia
author_sort	Shobana V. Stassen
title	Generalized and scalable trajectory inference in single-cell omics data with VIA
title_short	Generalized and scalable trajectory inference in single-cell omics data with VIA
title_full	Generalized and scalable trajectory inference in single-cell omics data with VIA
title_fullStr	Generalized and scalable trajectory inference in single-cell omics data with VIA
title_full_unstemmed	Generalized and scalable trajectory inference in single-cell omics data with VIA
title_sort	generalized and scalable trajectory inference in single-cell omics data with via
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9bd006f35d39495d922c8c86b7b6b9a2
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Generalized and scalable trajectory inference in single-cell omics data with VIA

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