Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years

Mengmeng Chen, Ruideng Wang, Pu Jia, Li Bao, Hai Tang Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Hai TangDepartment of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, No. 95,...

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Autores principales:	Chen M, Wang R, Jia P, Bao L, Tang H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	stentoplasty vertebral compression fracture filler material bone fillers osteogenesis. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/9bdf465bd7c340d09f36cb740bf2e865
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spelling	oai:doaj.org-article:9bdf465bd7c340d09f36cb740bf2e8652021-12-02T15:55:50ZStentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years1178-1998https://doaj.org/article/9bdf465bd7c340d09f36cb740bf2e8652021-05-01T00:00:00Zhttps://www.dovepress.com/stentoplasty-with-resorbable-calcium-salt-bone-void-fillers-for-the-tr-peer-reviewed-fulltext-article-CIAhttps://doaj.org/toc/1178-1998Mengmeng Chen, Ruideng Wang, Pu Jia, Li Bao, Hai Tang Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Hai TangDepartment of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong an Road, XiCheng District, Beijing, 100050, People’s Republic of ChinaTel +861 360 136 2187Email tanghai@ccmu.edu.cnPurpose: The aim of the study is to investigate the clinical and radiological outcomes of vertebral compression fractures treated by stentoplasty with resorbable calcium salt bone void fillers compared with balloon kyphoplasty (BKP).Methods: This prospective study included patients with fresh mono-thoracolumbar vertebral compression fractures. Patients enrolled were randomly divided into three groups. The patients in group A underwent stentoplasty with calcium sulfate/calcium phosphate (CSCP) composite filler and patients in group B with hydroxyapatite/collagen (HAP/COL) composite filler, while patients in group C underwent BKP with polymethylmethacrylate (PMMA). The clinical outcome was evaluated with visual analogue pain scale (VAS) and Oswestry disability score (ODI). The radiological results were evaluated with anterior height (AH) and Cobb angle of vertebral body. Computed tomography (CT) was used to assess osteogenesis effect.Results: Each group included 14 patients. The VAS, ODI, Cobb angle and AH were statistically improved compared with preoperative and there was no significant difference between the three groups. However, the AH in group A and group B at 1-year follow-up presented slight loss compared with 1 day after surgery. CT results suggested both group A and group B presented obvious bone trabecula formation and variations of CT value.Conclusion: The stentoplasty with resorbable calcium salt bone void fillers demonstrated clinical outcomes similar to traditional BKP for vertebral compression fractures. Both HAP/COL and CSCP performed certain osteogenesis. However, stentoplasty with studied fillers showed slight loss of AH within 1 year after surgery.Keywords: stentoplasty, vertebral compression fracture, filler material, bone fillers, osteogenesisChen MWang RJia PBao LTang HDove Medical Pressarticlestentoplastyvertebral compression fracturefiller materialbone fillersosteogenesis.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 16, Pp 843-852 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	stentoplasty vertebral compression fracture filler material bone fillers osteogenesis. Geriatrics RC952-954.6
spellingShingle	stentoplasty vertebral compression fracture filler material bone fillers osteogenesis. Geriatrics RC952-954.6 Chen M Wang R Jia P Bao L Tang H Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
description	Mengmeng Chen, Ruideng Wang, Pu Jia, Li Bao, Hai Tang Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Hai TangDepartment of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong an Road, XiCheng District, Beijing, 100050, People’s Republic of ChinaTel +861 360 136 2187Email tanghai@ccmu.edu.cnPurpose: The aim of the study is to investigate the clinical and radiological outcomes of vertebral compression fractures treated by stentoplasty with resorbable calcium salt bone void fillers compared with balloon kyphoplasty (BKP).Methods: This prospective study included patients with fresh mono-thoracolumbar vertebral compression fractures. Patients enrolled were randomly divided into three groups. The patients in group A underwent stentoplasty with calcium sulfate/calcium phosphate (CSCP) composite filler and patients in group B with hydroxyapatite/collagen (HAP/COL) composite filler, while patients in group C underwent BKP with polymethylmethacrylate (PMMA). The clinical outcome was evaluated with visual analogue pain scale (VAS) and Oswestry disability score (ODI). The radiological results were evaluated with anterior height (AH) and Cobb angle of vertebral body. Computed tomography (CT) was used to assess osteogenesis effect.Results: Each group included 14 patients. The VAS, ODI, Cobb angle and AH were statistically improved compared with preoperative and there was no significant difference between the three groups. However, the AH in group A and group B at 1-year follow-up presented slight loss compared with 1 day after surgery. CT results suggested both group A and group B presented obvious bone trabecula formation and variations of CT value.Conclusion: The stentoplasty with resorbable calcium salt bone void fillers demonstrated clinical outcomes similar to traditional BKP for vertebral compression fractures. Both HAP/COL and CSCP performed certain osteogenesis. However, stentoplasty with studied fillers showed slight loss of AH within 1 year after surgery.Keywords: stentoplasty, vertebral compression fracture, filler material, bone fillers, osteogenesis
format	article
author	Chen M Wang R Jia P Bao L Tang H
author_facet	Chen M Wang R Jia P Bao L Tang H
author_sort	Chen M
title	Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
title_short	Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
title_full	Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
title_fullStr	Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
title_full_unstemmed	Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years
title_sort	stentoplasty with resorbable calcium salt bone void fillers for the treatment of vertebral compression fracture: evaluation after 3 years
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/9bdf465bd7c340d09f36cb740bf2e865
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Stentoplasty with Resorbable Calcium Salt Bone Void Fillers for the Treatment of Vertebral Compression Fracture: Evaluation After 3 Years

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