Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length

Centrioles and cilia are microtubule-based structures of defined architecture, but what regulates this architecture is not clear. Here the authors discover that centrosomal-P4.1-associated-protein (CPAP) binds the α/β-tubulin dimer and licenses it for tubulin delivery contributing to centriolar/cili...

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Auteurs principaux:	Xiangdong Zheng, Anand Ramani, Komal Soni, Marco Gottardo, Shuangping Zheng, Li Ming Gooi, Wenjing Li, Shan Feng, Aruljothi Mariappan, Arpit Wason, Per Widlund, Andrei Pozniakovsky, Ina Poser, Haiteng Deng, Guangshuo Ou, Maria Riparbelli, Callaini Giuliano, Anthony A. Hyman, Michael Sattler, Jay Gopalakrishnan, Haitao Li
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/9be27009a3e84a74ac5a9cc418b64bae
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Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length

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