The epigenomic landscape of transposable elements across normal human development and anatomy

Although most are silenced, certain transposable elements (TEs) have been co-opted by the host. Here, the authors quantify the epigenomic status of TEs using data from the Roadmap Epigenomics Project, provide a systematic profile of TE activity across normal human tissues and development, finding th...

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Autores principales:	Erica C. Pehrsson, Mayank N. K. Choudhary, Vasavi Sundaram, Ting Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9be8243c98f04693903b38c681d2a1b9
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spelling	oai:doaj.org-article:9be8243c98f04693903b38c681d2a1b92021-12-02T16:57:42ZThe epigenomic landscape of transposable elements across normal human development and anatomy10.1038/s41467-019-13555-x2041-1723https://doaj.org/article/9be8243c98f04693903b38c681d2a1b92019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13555-xhttps://doaj.org/toc/2041-1723Although most are silenced, certain transposable elements (TEs) have been co-opted by the host. Here, the authors quantify the epigenomic status of TEs using data from the Roadmap Epigenomics Project, provide a systematic profile of TE activity across normal human tissues and development, finding that TEs encompass a quarter of the human regulatory epigenome, with 47% of TEs in regulatory states.Erica C. PehrssonMayank N. K. ChoudharyVasavi SundaramTing WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erica C. Pehrsson Mayank N. K. Choudhary Vasavi Sundaram Ting Wang The epigenomic landscape of transposable elements across normal human development and anatomy
description	Although most are silenced, certain transposable elements (TEs) have been co-opted by the host. Here, the authors quantify the epigenomic status of TEs using data from the Roadmap Epigenomics Project, provide a systematic profile of TE activity across normal human tissues and development, finding that TEs encompass a quarter of the human regulatory epigenome, with 47% of TEs in regulatory states.
format	article
author	Erica C. Pehrsson Mayank N. K. Choudhary Vasavi Sundaram Ting Wang
author_facet	Erica C. Pehrsson Mayank N. K. Choudhary Vasavi Sundaram Ting Wang
author_sort	Erica C. Pehrsson
title	The epigenomic landscape of transposable elements across normal human development and anatomy
title_short	The epigenomic landscape of transposable elements across normal human development and anatomy
title_full	The epigenomic landscape of transposable elements across normal human development and anatomy
title_fullStr	The epigenomic landscape of transposable elements across normal human development and anatomy
title_full_unstemmed	The epigenomic landscape of transposable elements across normal human development and anatomy
title_sort	epigenomic landscape of transposable elements across normal human development and anatomy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9be8243c98f04693903b38c681d2a1b9
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_version_	1718382516958658560

The epigenomic landscape of transposable elements across normal human development and anatomy

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