GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides.

GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides.

<h4>Background</h4>TGFß overproduction in cancer cells is one of the main characteristics of late tumor progression being implicated in metastasis, tumor growth, angiogenesis and immune response. We investigated the therapeutic efficacy of anti-TGFß peptides in the control of angiogenesi...

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Autores principales: Francesca Margheri, Nicola Schiavone, Laura Papucci, Lucia Magnelli, Simona Serratì, Anastasia Chillà, Anna Laurenzana, Francesca Bianchini, Lido Calorini, Eugenio Torre, Javier Dotor, Esperanza Feijoo, Gabriella Fibbi, Mario Del Rosso
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9be95842e3a64f8a9bd8cf6d6c21ae83
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