DNA–protein crosslink proteases in genome stability

DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.

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Autores principales: Annamaria Ruggiano, Kristijan Ramadan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9bee877057934c8eb531024e1fe21fbc
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spelling oai:doaj.org-article:9bee877057934c8eb531024e1fe21fbc2021-12-02T15:13:13ZDNA–protein crosslink proteases in genome stability10.1038/s42003-020-01539-32399-3642https://doaj.org/article/9bee877057934c8eb531024e1fe21fbc2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01539-3https://doaj.org/toc/2399-3642DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.Annamaria RuggianoKristijan RamadanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Annamaria Ruggiano
Kristijan Ramadan
DNA–protein crosslink proteases in genome stability
description DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.
format article
author Annamaria Ruggiano
Kristijan Ramadan
author_facet Annamaria Ruggiano
Kristijan Ramadan
author_sort Annamaria Ruggiano
title DNA–protein crosslink proteases in genome stability
title_short DNA–protein crosslink proteases in genome stability
title_full DNA–protein crosslink proteases in genome stability
title_fullStr DNA–protein crosslink proteases in genome stability
title_full_unstemmed DNA–protein crosslink proteases in genome stability
title_sort dna–protein crosslink proteases in genome stability
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9bee877057934c8eb531024e1fe21fbc
work_keys_str_mv AT annamariaruggiano dnaproteincrosslinkproteasesingenomestability
AT kristijanramadan dnaproteincrosslinkproteasesingenomestability
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