DNA–protein crosslink proteases in genome stability
DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.
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Nature Portfolio
2021
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oai:doaj.org-article:9bee877057934c8eb531024e1fe21fbc2021-12-02T15:13:13ZDNA–protein crosslink proteases in genome stability10.1038/s42003-020-01539-32399-3642https://doaj.org/article/9bee877057934c8eb531024e1fe21fbc2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01539-3https://doaj.org/toc/2399-3642DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond.Annamaria RuggianoKristijan RamadanNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021) |
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DOAJ |
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DOAJ |
language |
EN |
topic |
Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Annamaria Ruggiano Kristijan Ramadan DNA–protein crosslink proteases in genome stability |
description |
DNA–protein crosslink (DPC) proteases digest the protein component of crosslinks that otherwise can cause genomic instability and disease. Ruggiano and Ramadan discuss recent insights into the roles of DPC proteases in the repair of DPCs and beyond. |
format |
article |
author |
Annamaria Ruggiano Kristijan Ramadan |
author_facet |
Annamaria Ruggiano Kristijan Ramadan |
author_sort |
Annamaria Ruggiano |
title |
DNA–protein crosslink proteases in genome stability |
title_short |
DNA–protein crosslink proteases in genome stability |
title_full |
DNA–protein crosslink proteases in genome stability |
title_fullStr |
DNA–protein crosslink proteases in genome stability |
title_full_unstemmed |
DNA–protein crosslink proteases in genome stability |
title_sort |
dna–protein crosslink proteases in genome stability |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/9bee877057934c8eb531024e1fe21fbc |
work_keys_str_mv |
AT annamariaruggiano dnaproteincrosslinkproteasesingenomestability AT kristijanramadan dnaproteincrosslinkproteasesingenomestability |
_version_ |
1718387586660040704 |