Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism

In some parasites, membrane-bound pyrophosphatases, which couple proton and sodium ion transport across the membrane, are important for infectivity. Here, the authors report crystal structures of these proteins alongside biophysical analyses that allow them to propose a model for how the coupling is...

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Autores principales:	Kun-Mou Li, Craig Wilkinson, Juho Kellosalo, Jia-Yin Tsai, Tommi Kajander, Lars J. C. Jeuken, Yuh-Ju Sun, Adrian Goldman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9bf03144000f411fad9765f84873b5f9
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spelling	oai:doaj.org-article:9bf03144000f411fad9765f84873b5f92021-12-02T14:39:15ZMembrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism10.1038/ncomms135962041-1723https://doaj.org/article/9bf03144000f411fad9765f84873b5f92016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13596https://doaj.org/toc/2041-1723In some parasites, membrane-bound pyrophosphatases, which couple proton and sodium ion transport across the membrane, are important for infectivity. Here, the authors report crystal structures of these proteins alongside biophysical analyses that allow them to propose a model for how the coupling is achieved.Kun-Mou LiCraig WilkinsonJuho KellosaloJia-Yin TsaiTommi KajanderLars J. C. JeukenYuh-Ju SunAdrian GoldmanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kun-Mou Li Craig Wilkinson Juho Kellosalo Jia-Yin Tsai Tommi Kajander Lars J. C. Jeuken Yuh-Ju Sun Adrian Goldman Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
description	In some parasites, membrane-bound pyrophosphatases, which couple proton and sodium ion transport across the membrane, are important for infectivity. Here, the authors report crystal structures of these proteins alongside biophysical analyses that allow them to propose a model for how the coupling is achieved.
format	article
author	Kun-Mou Li Craig Wilkinson Juho Kellosalo Jia-Yin Tsai Tommi Kajander Lars J. C. Jeuken Yuh-Ju Sun Adrian Goldman
author_facet	Kun-Mou Li Craig Wilkinson Juho Kellosalo Jia-Yin Tsai Tommi Kajander Lars J. C. Jeuken Yuh-Ju Sun Adrian Goldman
author_sort	Kun-Mou Li
title	Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
title_short	Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
title_full	Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
title_fullStr	Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
title_full_unstemmed	Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism
title_sort	membrane pyrophosphatases from thermotoga maritima and vigna radiata suggest a conserved coupling mechanism
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9bf03144000f411fad9765f84873b5f9
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Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism

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