Urinary iodine as an important indicator for preeclampsia: a Polish perspective

Preeclampsia (PE) is one of the leading causes of perinatal and maternal morbidity. Although subclinical hypothyroidism in pregnancy is one of the established risk factors for PE, the link between iodine deficiency and PE is not fully understood. The aim of our study was to assess urinary iodine con...

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Autores principales:	Gajewska Katarzyna, Laskowska Marzena, Blazewicz Anna
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	iodine preeclampsia pregnancy Medicine R
Acceso en línea:	https://doaj.org/article/9bf698971ff94341bf76b942fc06a11e
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spelling	oai:doaj.org-article:9bf698971ff94341bf76b942fc06a11e2021-12-05T14:11:06ZUrinary iodine as an important indicator for preeclampsia: a Polish perspective2300-667610.2478/cipms-2021-0023https://doaj.org/article/9bf698971ff94341bf76b942fc06a11e2021-09-01T00:00:00Zhttps://doi.org/10.2478/cipms-2021-0023https://doaj.org/toc/2300-6676Preeclampsia (PE) is one of the leading causes of perinatal and maternal morbidity. Although subclinical hypothyroidism in pregnancy is one of the established risk factors for PE, the link between iodine deficiency and PE is not fully understood. The aim of our study was to assess urinary iodine concentration (UIC), serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), and free thyroxine (fT4) levels in Polish women with PE (PE group, n=78) compared with healthy non-pregnant women (CNP group, n=30), and healthy pregnant women (CP group, n=46). The UIC was determined by inductively coupled plasma mass spectrometry (ICP-MS). Both the mean UIC of 144.6±36.4 μg/L in the CP group and the mean of 125.8±33.6 μg/L in the PE group, respectively, were lower compared to non-pregnant women (149.8±28.8 μg/L), and the difference between the PE and CNP groups was statistically significant. TSH values were the highest in the PE group, while the lowest average level was for the CNP group. The fT3 and fT4 values in the PE group were significantly lower compared to the CNP and CP groups. Despite iodine supplementation during pregnancy, the UIC was lower compared to non-pregnant women, while in women with PE it was at a significantly lower level. To reduce the incidence of possible health complications, proper iodine supplementation and monitoring of the UIC is recommended for pregnant women suffering from PE or at risk of developing PE.Gajewska KatarzynaLaskowska MarzenaBlazewicz AnnaSciendoarticleiodinepreeclampsiapregnancyMedicineRENCurrent Issues in Pharmacy and Medical Sciences, Vol 34, Iss 3, Pp 154-159 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	iodine preeclampsia pregnancy Medicine R
spellingShingle	iodine preeclampsia pregnancy Medicine R Gajewska Katarzyna Laskowska Marzena Blazewicz Anna Urinary iodine as an important indicator for preeclampsia: a Polish perspective
description	Preeclampsia (PE) is one of the leading causes of perinatal and maternal morbidity. Although subclinical hypothyroidism in pregnancy is one of the established risk factors for PE, the link between iodine deficiency and PE is not fully understood. The aim of our study was to assess urinary iodine concentration (UIC), serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), and free thyroxine (fT4) levels in Polish women with PE (PE group, n=78) compared with healthy non-pregnant women (CNP group, n=30), and healthy pregnant women (CP group, n=46). The UIC was determined by inductively coupled plasma mass spectrometry (ICP-MS). Both the mean UIC of 144.6±36.4 μg/L in the CP group and the mean of 125.8±33.6 μg/L in the PE group, respectively, were lower compared to non-pregnant women (149.8±28.8 μg/L), and the difference between the PE and CNP groups was statistically significant. TSH values were the highest in the PE group, while the lowest average level was for the CNP group. The fT3 and fT4 values in the PE group were significantly lower compared to the CNP and CP groups. Despite iodine supplementation during pregnancy, the UIC was lower compared to non-pregnant women, while in women with PE it was at a significantly lower level. To reduce the incidence of possible health complications, proper iodine supplementation and monitoring of the UIC is recommended for pregnant women suffering from PE or at risk of developing PE.
format	article
author	Gajewska Katarzyna Laskowska Marzena Blazewicz Anna
author_facet	Gajewska Katarzyna Laskowska Marzena Blazewicz Anna
author_sort	Gajewska Katarzyna
title	Urinary iodine as an important indicator for preeclampsia: a Polish perspective
title_short	Urinary iodine as an important indicator for preeclampsia: a Polish perspective
title_full	Urinary iodine as an important indicator for preeclampsia: a Polish perspective
title_fullStr	Urinary iodine as an important indicator for preeclampsia: a Polish perspective
title_full_unstemmed	Urinary iodine as an important indicator for preeclampsia: a Polish perspective
title_sort	urinary iodine as an important indicator for preeclampsia: a polish perspective
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/9bf698971ff94341bf76b942fc06a11e
work_keys_str_mv	AT gajewskakatarzyna urinaryiodineasanimportantindicatorforpreeclampsiaapolishperspective AT laskowskamarzena urinaryiodineasanimportantindicatorforpreeclampsiaapolishperspective AT blazewiczanna urinaryiodineasanimportantindicatorforpreeclampsiaapolishperspective
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Urinary iodine as an important indicator for preeclampsia: a Polish perspective

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