Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

How microglia contribute to brain injury or repair is unclear. Here combining microglia manipulations and calcium imaging, the authors show that selective elimination of microglia leads to disrupted neuronal calcium dynamics and markedly increased brain injury after cerebral ischemia.

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Detalles Bibliográficos
Autores principales: Gergely Szalay, Bernadett Martinecz, Nikolett Lénárt, Zsuzsanna Környei, Barbara Orsolits, Linda Judák, Eszter Császár, Rebeka Fekete, Brian L. West, Gergely Katona, Balázs Rózsa, Ádám Dénes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9bfaf3e021e14db6b290d94b1ef5a607
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