GroEL/ES mediated the in vivo recovery of TRAIL inclusion bodies in Escherichia coli

Abstract Inclusion body (IB) formation generates substantial bio-waste in the pharmaceutical industry and remains a major challenge for heterologous protein expression. Although chaperones can be co-expressed to improve soluble protein yield, their contribution to IB processing in vivo has not been...

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Bibliographic Details
Main Authors: Zhanqing Wang, Min Zhang, Xin Lv, Jiying Fan, Jian Zhang, Jing Sun, Yaling Shen
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/9c001b387a9d4afc83e57e681db6a0bc
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