In Vitro 3D <i>Staphylococcus aureus</i> Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells

In Vitro 3D <i>Staphylococcus aureus</i> Abscess Communities Induce Bone Marrow Cells to Expand into Myeloid-Derived Suppressor Cells

<i>Staphylococcus aureus</i> is the main causative pathogen of subcutaneous, bone, and implant-related infections, forming structures known as staphylococcal abscess communities (SACs) within tissues that also contain immunosuppressive myeloid-derived suppressor cells (MDSCs). Although b...

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Autores principales: Marloes I. Hofstee, Anja Heider, Sonja Häckel, Caroline Constant, Martijn Riool, R. Geoff Richards, T. Fintan Moriarty, Sebastian A. J. Zaat
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
<i>Staphylococcus aureus</i>
staphylococcal abscess community
myeloid-derived suppressor cell
3D in vitro model
bone infection
host-pathogen interaction
Medicine
R
Acceso en línea:https://doaj.org/article/9c002aee20ab48efa46220de3f3e0464
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