A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis
Communication between endothelial leader and follower cells during collective cell migration is crucial for vascular development. Here, the authors show that PACSIN2 guides collective cell migration and angiogenesis by recruiting a protein trafficking complex to asymmetric cell-cell junctions, contr...
Guardado en:
Autores principales: | Tsveta S. Malinova, Ana Angulo-Urarte, Julian Nüchel, Marina Tauber, Miesje M. van der Stoel, Vera Janssen, Annett de Haan, Anouk G. Groenen, Merel Tebbens, Mariona Graupera, Markus Plomann, Stephan Huveneers |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9c03eff830ca43ef9a69c069eaae2835 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions
por: Yvonne L. Dorland, et al.
Publicado: (2016) -
Catastrophic disassembly of actin filaments via Mical-mediated oxidation
por: Elena E. Grintsevich, et al.
Publicado: (2017) -
Experimental Study of Starvation and Flow Behavior in Grease-Lubricated EHD Contact
por: Jing Chen, et al.
Publicado: (2015) -
Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
por: Elena E. Grintsevich, et al.
Publicado: (2021) -
ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling
por: Raunaq Deo, et al.
Publicado: (2018)