Basic reinfection number and backward bifurcation

Some epidemiological models exhibit bi-stable dynamics even when the basic reproduction number $ {{{\cal R}_{0}}} $ is below $ 1 $, through a phenomenon known as a backward bifurcation. Causes for this phenomenon include exogenous reinfection, super-infection, relapse, vaccination exercises, heterog...

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Autor principal: Baojun Song
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Publicado: AIMS Press 2021
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spelling oai:doaj.org-article:9c09ab7947d448e1b20a12eaf0baad162021-11-23T03:06:23ZBasic reinfection number and backward bifurcation10.3934/mbe.20214001551-0018https://doaj.org/article/9c09ab7947d448e1b20a12eaf0baad162021-09-01T00:00:00Zhttps://www.aimspress.com/article/doi/10.3934/mbe.2021400?viewType=HTMLhttps://doaj.org/toc/1551-0018Some epidemiological models exhibit bi-stable dynamics even when the basic reproduction number $ {{{\cal R}_{0}}} $ is below $ 1 $, through a phenomenon known as a backward bifurcation. Causes for this phenomenon include exogenous reinfection, super-infection, relapse, vaccination exercises, heterogeneity among subpopulations, etc. To measure the reinfection forces, this paper defines a second threshold: the basic reinfection number. This number characterizes the type of bifurcation when the basic reproduction number is equal to one. If the basic reinfection number is greater than one, the bifurcation is backward. Otherwise it is forward. The basic reinfection number with the basic reproduction number together gives a complete measure for disease control whenever reinfections (or relapses) matter. We formulate the basic reinfection number for a variety of epidemiological models. Baojun Song AIMS Pressarticledisease dynamicsdifferential equationsbifurcationbasic reinfection numberBiotechnologyTP248.13-248.65MathematicsQA1-939ENMathematical Biosciences and Engineering, Vol 18, Iss 6, Pp 8064-8083 (2021)
institution DOAJ
collection DOAJ
language EN
topic disease dynamics
differential equations
bifurcation
basic reinfection number
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
spellingShingle disease dynamics
differential equations
bifurcation
basic reinfection number
Biotechnology
TP248.13-248.65
Mathematics
QA1-939
Baojun Song
Basic reinfection number and backward bifurcation
description Some epidemiological models exhibit bi-stable dynamics even when the basic reproduction number $ {{{\cal R}_{0}}} $ is below $ 1 $, through a phenomenon known as a backward bifurcation. Causes for this phenomenon include exogenous reinfection, super-infection, relapse, vaccination exercises, heterogeneity among subpopulations, etc. To measure the reinfection forces, this paper defines a second threshold: the basic reinfection number. This number characterizes the type of bifurcation when the basic reproduction number is equal to one. If the basic reinfection number is greater than one, the bifurcation is backward. Otherwise it is forward. The basic reinfection number with the basic reproduction number together gives a complete measure for disease control whenever reinfections (or relapses) matter. We formulate the basic reinfection number for a variety of epidemiological models.
format article
author Baojun Song
author_facet Baojun Song
author_sort Baojun Song
title Basic reinfection number and backward bifurcation
title_short Basic reinfection number and backward bifurcation
title_full Basic reinfection number and backward bifurcation
title_fullStr Basic reinfection number and backward bifurcation
title_full_unstemmed Basic reinfection number and backward bifurcation
title_sort basic reinfection number and backward bifurcation
publisher AIMS Press
publishDate 2021
url https://doaj.org/article/9c09ab7947d448e1b20a12eaf0baad16
work_keys_str_mv AT baojunsong basicreinfectionnumberandbackwardbifurcation
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