Fluorescent Biosensors Based on Silicon Nanowires

Nanostructures are arising as novel biosensing platforms promising to surpass current performance in terms of sensitivity, selectivity, and affordability of standard approaches. However, for several nanosensors, the material and synthesis used make the industrial transfer of such technologies comple...

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Autores principales: Antonio Alessio Leonardi, Maria José Lo Faro, Barbara Fazio, Corrado Spinella, Sabrina Conoci, Patrizia Livreri, Alessia Irrera
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:9c0bf9c07ba44b79b99fb589c631936d2021-11-25T18:31:17ZFluorescent Biosensors Based on Silicon Nanowires10.3390/nano111129702079-4991https://doaj.org/article/9c0bf9c07ba44b79b99fb589c631936d2021-11-01T00:00:00Zhttps://www.mdpi.com/2079-4991/11/11/2970https://doaj.org/toc/2079-4991Nanostructures are arising as novel biosensing platforms promising to surpass current performance in terms of sensitivity, selectivity, and affordability of standard approaches. However, for several nanosensors, the material and synthesis used make the industrial transfer of such technologies complex. Silicon nanowires (NWs) are compatible with Si-based flat architecture fabrication and arise as a hopeful solution to couple their interesting physical properties and surface-to-volume ratio to an easy commercial transfer. Among all the transduction methods, fluorescent probes and sensors emerge as some of the most used approaches thanks to their easy data interpretation, measure affordability, and real-time in situ analysis. In fluorescent sensors, Si NWs are employed as substrate and coupled with several fluorophores, NWs can be used as quenchers in stem-loop configuration, and have recently been used for direct fluorescent sensing. In this review, an overview on fluorescent sensors based on Si NWs is presented, analyzing the literature of the field and highlighting the advantages and drawbacks for each strategy.Antonio Alessio LeonardiMaria José Lo FaroBarbara FazioCorrado SpinellaSabrina ConociPatrizia LivreriAlessia IrreraMDPI AGarticlesilicon nanowiresfluorescent sensorsbiosensorslight-emissionChemistryQD1-999ENNanomaterials, Vol 11, Iss 2970, p 2970 (2021)
institution DOAJ
collection DOAJ
language EN
topic silicon nanowires
fluorescent sensors
biosensors
light-emission
Chemistry
QD1-999
spellingShingle silicon nanowires
fluorescent sensors
biosensors
light-emission
Chemistry
QD1-999
Antonio Alessio Leonardi
Maria José Lo Faro
Barbara Fazio
Corrado Spinella
Sabrina Conoci
Patrizia Livreri
Alessia Irrera
Fluorescent Biosensors Based on Silicon Nanowires
description Nanostructures are arising as novel biosensing platforms promising to surpass current performance in terms of sensitivity, selectivity, and affordability of standard approaches. However, for several nanosensors, the material and synthesis used make the industrial transfer of such technologies complex. Silicon nanowires (NWs) are compatible with Si-based flat architecture fabrication and arise as a hopeful solution to couple their interesting physical properties and surface-to-volume ratio to an easy commercial transfer. Among all the transduction methods, fluorescent probes and sensors emerge as some of the most used approaches thanks to their easy data interpretation, measure affordability, and real-time in situ analysis. In fluorescent sensors, Si NWs are employed as substrate and coupled with several fluorophores, NWs can be used as quenchers in stem-loop configuration, and have recently been used for direct fluorescent sensing. In this review, an overview on fluorescent sensors based on Si NWs is presented, analyzing the literature of the field and highlighting the advantages and drawbacks for each strategy.
format article
author Antonio Alessio Leonardi
Maria José Lo Faro
Barbara Fazio
Corrado Spinella
Sabrina Conoci
Patrizia Livreri
Alessia Irrera
author_facet Antonio Alessio Leonardi
Maria José Lo Faro
Barbara Fazio
Corrado Spinella
Sabrina Conoci
Patrizia Livreri
Alessia Irrera
author_sort Antonio Alessio Leonardi
title Fluorescent Biosensors Based on Silicon Nanowires
title_short Fluorescent Biosensors Based on Silicon Nanowires
title_full Fluorescent Biosensors Based on Silicon Nanowires
title_fullStr Fluorescent Biosensors Based on Silicon Nanowires
title_full_unstemmed Fluorescent Biosensors Based on Silicon Nanowires
title_sort fluorescent biosensors based on silicon nanowires
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/9c0bf9c07ba44b79b99fb589c631936d
work_keys_str_mv AT antonioalessioleonardi fluorescentbiosensorsbasedonsiliconnanowires
AT mariajoselofaro fluorescentbiosensorsbasedonsiliconnanowires
AT barbarafazio fluorescentbiosensorsbasedonsiliconnanowires
AT corradospinella fluorescentbiosensorsbasedonsiliconnanowires
AT sabrinaconoci fluorescentbiosensorsbasedonsiliconnanowires
AT patrizialivreri fluorescentbiosensorsbasedonsiliconnanowires
AT alessiairrera fluorescentbiosensorsbasedonsiliconnanowires
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