Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy
Some chemotherapeutic drugs, such as doxorubicin, induce immunogenic cell death (ICD) and promote anti-tumor immune responses. Here the authors report that the histone demethylase inhibitor 5-carboxy-8-hydroxyquinoline (IOX1) reduces the expression of PD-L1 in cancer cells and enhances doxorubicin-i...
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Autores principales: | Jing Liu, Zhihao Zhao, Nasha Qiu, Quan Zhou, Guowei Wang, Haiping Jiang, Ying Piao, Zhuxian Zhou, Jianbin Tang, Youqing Shen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9c13235dc1e945df90f7c6920d76d06e |
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