FMN reduces Amyloid-β toxicity in yeast by regulating redox status and cellular metabolism
Saccharomyces cerevisiae is a model organism to study proteins involved in neurodegeneration. Here, the authors performed a yeast genome-wide synthetic genetic interaction array (SGA) to screen for toxicity modifiers of Aβ42 and identify riboflavin kinase and its metabolic product flavin mononucleot...
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Autores principales: | Xin Chen, Boyang Ji, Xinxin Hao, Xiaowei Li, Frederik Eisele, Thomas Nyström, Dina Petranovic |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/9c14572cb31348da8b839cc360d90b92 |
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