Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination
Disruption or loss of oligodendrocytes (OLs) and myelin has devastating effects on CNS function and integrity, which occur in diverse neurological disorders, including Multiple Sclerosis (MS), Alzheimer’s disease and neuropsychiatric disorders. Hence, there is a need to develop new therapies that pr...
Guardado en:
Autores principales: | A.D. Rivera, F. Pieropan, G. Williams, F. Calzolari, A.M. Butt, K. Azim |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9c39d9c18650411aa069869eba42e464 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A developmental approach to homology and brain evolution
por: ABOITIZ,FRANCISCO
Publicado: (2010) -
Evolutionary Origins of the Oligodendrocyte Cell Type and Adaptive Myelination
por: Jacob H. Hines
Publicado: (2021) -
“FlashMap” - A Semi-Automatic Tool for Rapid and Accurate Spatial Analysis of Marker Expression in the Subventricular Zone
por: Stefan Zweifel, et al.
Publicado: (2018) -
Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases
por: Luana C. Soares, et al.
Publicado: (2021) -
Replenishing the Aged Brains: Targeting Oligodendrocytes and Myelination?
por: Xi Zhang, et al.
Publicado: (2021)