High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

Optogenetic applications would benefit from channelrhodopsins (ChRs) with faster photostimulation, increased tissue transparency and lower phototoxicity. Here, the authors develop fast red-shifted ChR variants and show the abilities for temporal precise spiking of cerebral interneurons and restoring...

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Autores principales:	Thomas Mager, David Lopez de la Morena, Verena Senn, Johannes Schlotte, Anna D´Errico, Katrin Feldbauer, Christian Wrobel, Sangyong Jung, Kai Bodensiek, Vladan Rankovic, Lorcan Browne, Antoine Huet, Josephine Jüttner, Phillip G. Wood, Johannes J. Letzkus, Tobias Moser, Ernst Bamberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9c3dadccba5843fba489be7c07b640fb
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spelling	oai:doaj.org-article:9c3dadccba5843fba489be7c07b640fb2021-12-02T16:49:36ZHigh frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics10.1038/s41467-018-04146-32041-1723https://doaj.org/article/9c3dadccba5843fba489be7c07b640fb2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04146-3https://doaj.org/toc/2041-1723Optogenetic applications would benefit from channelrhodopsins (ChRs) with faster photostimulation, increased tissue transparency and lower phototoxicity. Here, the authors develop fast red-shifted ChR variants and show the abilities for temporal precise spiking of cerebral interneurons and restoring auditory activity in deaf mice.Thomas MagerDavid Lopez de la MorenaVerena SennJohannes SchlotteAnna D´ErricoKatrin FeldbauerChristian WrobelSangyong JungKai BodensiekVladan RankovicLorcan BrowneAntoine HuetJosephine JüttnerPhillip G. WoodJohannes J. LetzkusTobias MoserErnst BambergNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Mager David Lopez de la Morena Verena Senn Johannes Schlotte Anna D´Errico Katrin Feldbauer Christian Wrobel Sangyong Jung Kai Bodensiek Vladan Rankovic Lorcan Browne Antoine Huet Josephine Jüttner Phillip G. Wood Johannes J. Letzkus Tobias Moser Ernst Bamberg High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
description	Optogenetic applications would benefit from channelrhodopsins (ChRs) with faster photostimulation, increased tissue transparency and lower phototoxicity. Here, the authors develop fast red-shifted ChR variants and show the abilities for temporal precise spiking of cerebral interneurons and restoring auditory activity in deaf mice.
format	article
author	Thomas Mager David Lopez de la Morena Verena Senn Johannes Schlotte Anna D´Errico Katrin Feldbauer Christian Wrobel Sangyong Jung Kai Bodensiek Vladan Rankovic Lorcan Browne Antoine Huet Josephine Jüttner Phillip G. Wood Johannes J. Letzkus Tobias Moser Ernst Bamberg
author_facet	Thomas Mager David Lopez de la Morena Verena Senn Johannes Schlotte Anna D´Errico Katrin Feldbauer Christian Wrobel Sangyong Jung Kai Bodensiek Vladan Rankovic Lorcan Browne Antoine Huet Josephine Jüttner Phillip G. Wood Johannes J. Letzkus Tobias Moser Ernst Bamberg
author_sort	Thomas Mager
title	High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
title_short	High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
title_full	High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
title_fullStr	High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
title_full_unstemmed	High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
title_sort	high frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9c3dadccba5843fba489be7c07b640fb
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High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

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