Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

Non-coding RNAs have been shown to be key components in translational regulation. Here the authors characterize long nucleolus specific lncRNA termed LoNA, identified to play a role in protein biosynthesis by inhibiting rRNA production and ribosome biosynthesis in nucleoli.

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Autores principales: Dingfeng Li, Juan Zhang, Ming Wang, Xiaohui Li, Huarui Gong, Huiping Tang, Lin Chen, Lili Wan, Qiang Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9c46dff0d82944de8252c3ecb5fd350c
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spelling oai:doaj.org-article:9c46dff0d82944de8252c3ecb5fd350c2021-12-02T14:40:44ZActivity dependent LoNA regulates translation by coordinating rRNA transcription and methylation10.1038/s41467-018-04072-42041-1723https://doaj.org/article/9c46dff0d82944de8252c3ecb5fd350c2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04072-4https://doaj.org/toc/2041-1723Non-coding RNAs have been shown to be key components in translational regulation. Here the authors characterize long nucleolus specific lncRNA termed LoNA, identified to play a role in protein biosynthesis by inhibiting rRNA production and ribosome biosynthesis in nucleoli.Dingfeng LiJuan ZhangMing WangXiaohui LiHuarui GongHuiping TangLin ChenLili WanQiang LiuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dingfeng Li
Juan Zhang
Ming Wang
Xiaohui Li
Huarui Gong
Huiping Tang
Lin Chen
Lili Wan
Qiang Liu
Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
description Non-coding RNAs have been shown to be key components in translational regulation. Here the authors characterize long nucleolus specific lncRNA termed LoNA, identified to play a role in protein biosynthesis by inhibiting rRNA production and ribosome biosynthesis in nucleoli.
format article
author Dingfeng Li
Juan Zhang
Ming Wang
Xiaohui Li
Huarui Gong
Huiping Tang
Lin Chen
Lili Wan
Qiang Liu
author_facet Dingfeng Li
Juan Zhang
Ming Wang
Xiaohui Li
Huarui Gong
Huiping Tang
Lin Chen
Lili Wan
Qiang Liu
author_sort Dingfeng Li
title Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
title_short Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
title_full Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
title_fullStr Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
title_full_unstemmed Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
title_sort activity dependent lona regulates translation by coordinating rrna transcription and methylation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9c46dff0d82944de8252c3ecb5fd350c
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AT xiaohuili activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
AT huaruigong activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
AT huipingtang activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
AT linchen activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
AT liliwan activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
AT qiangliu activitydependentlonaregulatestranslationbycoordinatingrrnatranscriptionandmethylation
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