Transplanted interneurons improve memory precision after traumatic brain injury
The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.
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Nature Portfolio
2019
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oai:doaj.org-article:9c4c6665ee2c41a9a69ba34e7a00670f2021-12-02T17:32:09ZTransplanted interneurons improve memory precision after traumatic brain injury10.1038/s41467-019-13170-w2041-1723https://doaj.org/article/9c4c6665ee2c41a9a69ba34e7a00670f2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13170-whttps://doaj.org/toc/2041-1723The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.Bingyao ZhuJisu EomRobert F. HuntNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Bingyao Zhu Jisu Eom Robert F. Hunt Transplanted interneurons improve memory precision after traumatic brain injury |
description |
The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury. |
format |
article |
author |
Bingyao Zhu Jisu Eom Robert F. Hunt |
author_facet |
Bingyao Zhu Jisu Eom Robert F. Hunt |
author_sort |
Bingyao Zhu |
title |
Transplanted interneurons improve memory precision after traumatic brain injury |
title_short |
Transplanted interneurons improve memory precision after traumatic brain injury |
title_full |
Transplanted interneurons improve memory precision after traumatic brain injury |
title_fullStr |
Transplanted interneurons improve memory precision after traumatic brain injury |
title_full_unstemmed |
Transplanted interneurons improve memory precision after traumatic brain injury |
title_sort |
transplanted interneurons improve memory precision after traumatic brain injury |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/9c4c6665ee2c41a9a69ba34e7a00670f |
work_keys_str_mv |
AT bingyaozhu transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury AT jisueom transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury AT robertfhunt transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury |
_version_ |
1718380386071871488 |