Transplanted interneurons improve memory precision after traumatic brain injury

The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.

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Autores principales: Bingyao Zhu, Jisu Eom, Robert F. Hunt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9c4c6665ee2c41a9a69ba34e7a00670f
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spelling oai:doaj.org-article:9c4c6665ee2c41a9a69ba34e7a00670f2021-12-02T17:32:09ZTransplanted interneurons improve memory precision after traumatic brain injury10.1038/s41467-019-13170-w2041-1723https://doaj.org/article/9c4c6665ee2c41a9a69ba34e7a00670f2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13170-whttps://doaj.org/toc/2041-1723The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.Bingyao ZhuJisu EomRobert F. HuntNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bingyao Zhu
Jisu Eom
Robert F. Hunt
Transplanted interneurons improve memory precision after traumatic brain injury
description The brain’s capacity to produce new neurons in response to injury is limited. Here, the authors transplant GABAergic progenitor cells and show that they synaptically incorporate into the damaged hippocampus and rescue memory problems and post-traumatic seizures caused by traumatic brain injury.
format article
author Bingyao Zhu
Jisu Eom
Robert F. Hunt
author_facet Bingyao Zhu
Jisu Eom
Robert F. Hunt
author_sort Bingyao Zhu
title Transplanted interneurons improve memory precision after traumatic brain injury
title_short Transplanted interneurons improve memory precision after traumatic brain injury
title_full Transplanted interneurons improve memory precision after traumatic brain injury
title_fullStr Transplanted interneurons improve memory precision after traumatic brain injury
title_full_unstemmed Transplanted interneurons improve memory precision after traumatic brain injury
title_sort transplanted interneurons improve memory precision after traumatic brain injury
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9c4c6665ee2c41a9a69ba34e7a00670f
work_keys_str_mv AT bingyaozhu transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury
AT jisueom transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury
AT robertfhunt transplantedinterneuronsimprovememoryprecisionaftertraumaticbraininjury
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