Sc-compReg enables the comparison of gene regulatory networks between conditions using single-cell data
Changes in cell state underlie the difference between health and disease. Here, the authors propose a computational framework for the integration of gene expression and chromatin-accessibility data from single cells to identify differences in gene regulation in cell types across two conditions.
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Autores principales: | Zhana Duren, Wenhui Sophia Lu, Joseph G. Arthur, Preyas Shah, Jingxue Xin, Francesca Meschi, Miranda Lin Li, Corey M. Nemec, Yifeng Yin, Wing Hung Wong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9c4fc70938c445fdbe6641ebdbf16cd2 |
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