Effect of chewing betel nut on the gut microbiota of Hainanese.

Betel nut chewing (BNC) is prevalent in South Asia and Southeast Asia. BNC can affect host health by modulating the gut microbiota. The aim of this study is to evaluate the effect of BNC on the gut microbiota of the host. Feces samples were obtained from 34 BNC individuals from Ledong and Lingshui,...

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Autores principales:	Li Ying, Yunjia Yang, Jun Zhou, Hairong Huang, Guankui Du
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9c5255f2b6d94ad8a28b5f63c377ce23
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spelling	oai:doaj.org-article:9c5255f2b6d94ad8a28b5f63c377ce232021-12-02T20:19:12ZEffect of chewing betel nut on the gut microbiota of Hainanese.1932-620310.1371/journal.pone.0258489https://doaj.org/article/9c5255f2b6d94ad8a28b5f63c377ce232021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0258489https://doaj.org/toc/1932-6203Betel nut chewing (BNC) is prevalent in South Asia and Southeast Asia. BNC can affect host health by modulating the gut microbiota. The aim of this study is to evaluate the effect of BNC on the gut microbiota of the host. Feces samples were obtained from 34 BNC individuals from Ledong and Lingshui, Hainan, China. The microbiota was analyzed by 16S rRNA gene sequencing. BNC decreased the microbial α-diversity. Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria were the predominant phyla, accounting for 99.35% of the BNC group. The Firmicutes-to-Bacteroidetes ratio was significantly increased in the BNC group compared to a control group. The abundances of the families Aerococcaceae, Neisseriaceae, Moraxellaceae, Porphyromonadaceae, and Planococcaceae were decreased in the BNC/BNC_Male/BNC_Female groups compared to the control group, whereas the abundances of Coriobacteriaceae, Streptococcaceae, Micrococcaceae, Xanthomonadaceae, Coxiellaceae, Nocardioidaceae, Rhodobacteraceae, and Succinivibrionaceae were increased. In general, the gut microbiome profiles suggest that BNC may have positive effects, such as an increase in the abundance of beneficial microbes and a reduction in the abundance of disease-related microbes. However, BNC may also produce an increase in the abundance of disease-related microbes. Therefore, extraction of prebiotic components could increase the beneficial value of betel nut.Li YingYunjia YangJun ZhouHairong HuangGuankui DuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0258489 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Li Ying Yunjia Yang Jun Zhou Hairong Huang Guankui Du Effect of chewing betel nut on the gut microbiota of Hainanese.
description	Betel nut chewing (BNC) is prevalent in South Asia and Southeast Asia. BNC can affect host health by modulating the gut microbiota. The aim of this study is to evaluate the effect of BNC on the gut microbiota of the host. Feces samples were obtained from 34 BNC individuals from Ledong and Lingshui, Hainan, China. The microbiota was analyzed by 16S rRNA gene sequencing. BNC decreased the microbial α-diversity. Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria were the predominant phyla, accounting for 99.35% of the BNC group. The Firmicutes-to-Bacteroidetes ratio was significantly increased in the BNC group compared to a control group. The abundances of the families Aerococcaceae, Neisseriaceae, Moraxellaceae, Porphyromonadaceae, and Planococcaceae were decreased in the BNC/BNC_Male/BNC_Female groups compared to the control group, whereas the abundances of Coriobacteriaceae, Streptococcaceae, Micrococcaceae, Xanthomonadaceae, Coxiellaceae, Nocardioidaceae, Rhodobacteraceae, and Succinivibrionaceae were increased. In general, the gut microbiome profiles suggest that BNC may have positive effects, such as an increase in the abundance of beneficial microbes and a reduction in the abundance of disease-related microbes. However, BNC may also produce an increase in the abundance of disease-related microbes. Therefore, extraction of prebiotic components could increase the beneficial value of betel nut.
format	article
author	Li Ying Yunjia Yang Jun Zhou Hairong Huang Guankui Du
author_facet	Li Ying Yunjia Yang Jun Zhou Hairong Huang Guankui Du
author_sort	Li Ying
title	Effect of chewing betel nut on the gut microbiota of Hainanese.
title_short	Effect of chewing betel nut on the gut microbiota of Hainanese.
title_full	Effect of chewing betel nut on the gut microbiota of Hainanese.
title_fullStr	Effect of chewing betel nut on the gut microbiota of Hainanese.
title_full_unstemmed	Effect of chewing betel nut on the gut microbiota of Hainanese.
title_sort	effect of chewing betel nut on the gut microbiota of hainanese.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/9c5255f2b6d94ad8a28b5f63c377ce23
work_keys_str_mv	AT liying effectofchewingbetelnutonthegutmicrobiotaofhainanese AT yunjiayang effectofchewingbetelnutonthegutmicrobiotaofhainanese AT junzhou effectofchewingbetelnutonthegutmicrobiotaofhainanese AT haironghuang effectofchewingbetelnutonthegutmicrobiotaofhainanese AT guankuidu effectofchewingbetelnutonthegutmicrobiotaofhainanese
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Effect of chewing betel nut on the gut microbiota of Hainanese.

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