Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to <italic toggle="yes">Clostridium difficile</italic> Virulence

ABSTRACT Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide diseas...

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Bibliographic Details
Main Authors: Brittany B. Lewis, Rebecca A. Carter, Lilan Ling, Ingrid Leiner, Ying Taur, Mini Kamboj, Erik R. Dubberke, Joao Xavier, Eric G. Pamer
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/9c54828146554dea95310db8ae19f8c7
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