Metabolic erosion primarily through mutation accumulation, and not tradeoffs, drives limited evolution of substrate specificity in Escherichia coli.
Evolutionary adaptation to a constant environment is often accompanied by specialization and a reduction of fitness in other environments. We assayed the ability of the Lenski Escherichia coli populations to grow on a range of carbon sources after 50,000 generations of adaptation on glucose. Using d...
Guardado en:
Autores principales: | Nicholas Leiby, Christopher J Marx |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/9c5cd7cb623a441abdf9fb88d7db39fd |
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