Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.
<h4>Background</h4>Important support functions, including promotion of tumor growth, angiogenesis, and invasion, have been attributed to the different cell types populating the tumor stroma, i.e., endothelial cells, cancer-associated fibroblasts, pericytes, and infiltrating inflammatory...
Guardado en:
Autores principales: | Kristian Pietras, Jessica Pahler, Gabriele Bergers, Douglas Hanahan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9c65748b24e944daa7f342557e9cccfa |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.
por: Elena I Fomchenko, et al.
Publicado: (2011) -
Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
por: Paulina Nastały, et al.
Publicado: (2021) -
Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors
por: Kayoko Hosaka, et al.
Publicado: (2020) -
Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells
por: Florian Wimmers, et al.
Publicado: (2018) -
Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours
por: Adama Sidibe, et al.
Publicado: (2018)