Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance

Processing bodies are phase separated compartments enriched in translationally repressed mRNAs. Here, Smith et al. show that, in sensory neurons, eukaryotic elongation factor 2 kinase (eEF2K) plays key roles in the regulation of processing body abundance and the formation of translationally inactive...

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Autores principales:	Patrick R. Smith, Sarah Loerch, Nikesh Kunder, Alexander D. Stanowick, Tzu-Fang Lou, Zachary T. Campbell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9c6a9fbaa8f14bc3a227f43bf19fed84
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spelling	oai:doaj.org-article:9c6a9fbaa8f14bc3a227f43bf19fed842021-11-28T12:32:48ZFunctionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance10.1038/s41467-021-27160-42041-1723https://doaj.org/article/9c6a9fbaa8f14bc3a227f43bf19fed842021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27160-4https://doaj.org/toc/2041-1723Processing bodies are phase separated compartments enriched in translationally repressed mRNAs. Here, Smith et al. show that, in sensory neurons, eukaryotic elongation factor 2 kinase (eEF2K) plays key roles in the regulation of processing body abundance and the formation of translationally inactive ribosomes.Patrick R. SmithSarah LoerchNikesh KunderAlexander D. StanowickTzu-Fang LouZachary T. CampbellNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Patrick R. Smith Sarah Loerch Nikesh Kunder Alexander D. Stanowick Tzu-Fang Lou Zachary T. Campbell Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
description	Processing bodies are phase separated compartments enriched in translationally repressed mRNAs. Here, Smith et al. show that, in sensory neurons, eukaryotic elongation factor 2 kinase (eEF2K) plays key roles in the regulation of processing body abundance and the formation of translationally inactive ribosomes.
format	article
author	Patrick R. Smith Sarah Loerch Nikesh Kunder Alexander D. Stanowick Tzu-Fang Lou Zachary T. Campbell
author_facet	Patrick R. Smith Sarah Loerch Nikesh Kunder Alexander D. Stanowick Tzu-Fang Lou Zachary T. Campbell
author_sort	Patrick R. Smith
title	Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
title_short	Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
title_full	Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
title_fullStr	Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
title_full_unstemmed	Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance
title_sort	functionally distinct roles for eef2k in the control of ribosome availability and p-body abundance
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9c6a9fbaa8f14bc3a227f43bf19fed84
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Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance

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