Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes
Abstract L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular mechanism remains obscure. Here we show the role of ascorbic acid in regulating epigenetic status of both nucleic acids and chromatin to promote oocyt...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/9c6bcaaac00a46d1b2edd0ae9f7c5c51 |
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