A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays

A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays

Many current immunoassays require multiple washing, incubation and optimization steps. Here the authors present Ratiometric Plug-and-Play Immunodiagnostics (RAPPID), a generic assay platform that uses ratiometric bioluminescent detection to allow sandwich immunoassays to be performed directly in sol...

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Autores principales: Yan Ni, Bas J. H. M. Rosier, Eva A. van Aalen, Eva T. L. Hanckmann, Lieuwe Biewenga, Anna-Maria Makri Pistikou, Bart Timmermans, Chris Vu, Sophie Roos, Remco Arts, Wentao Li, Tom F. A. de Greef, Marcel M. G. J. van Borren, Frank J. M. van Kuppeveld, Berend-Jan Bosch, Maarten Merkx
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9c6f00283d7b49f6a84e253e1ef16ce1
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Sumario:Many current immunoassays require multiple washing, incubation and optimization steps. Here the authors present Ratiometric Plug-and-Play Immunodiagnostics (RAPPID), a generic assay platform that uses ratiometric bioluminescent detection to allow sandwich immunoassays to be performed directly in solution.

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