A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays

A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays

Many current immunoassays require multiple washing, incubation and optimization steps. Here the authors present Ratiometric Plug-and-Play Immunodiagnostics (RAPPID), a generic assay platform that uses ratiometric bioluminescent detection to allow sandwich immunoassays to be performed directly in sol...

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Autores principales: Yan Ni, Bas J. H. M. Rosier, Eva A. van Aalen, Eva T. L. Hanckmann, Lieuwe Biewenga, Anna-Maria Makri Pistikou, Bart Timmermans, Chris Vu, Sophie Roos, Remco Arts, Wentao Li, Tom F. A. de Greef, Marcel M. G. J. van Borren, Frank J. M. van Kuppeveld, Berend-Jan Bosch, Maarten Merkx
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9c6f00283d7b49f6a84e253e1ef16ce1
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spelling oai:doaj.org-article:9c6f00283d7b49f6a84e253e1ef16ce12021-12-02T16:24:57ZA plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays10.1038/s41467-021-24874-32041-1723https://doaj.org/article/9c6f00283d7b49f6a84e253e1ef16ce12021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24874-3https://doaj.org/toc/2041-1723Many current immunoassays require multiple washing, incubation and optimization steps. Here the authors present Ratiometric Plug-and-Play Immunodiagnostics (RAPPID), a generic assay platform that uses ratiometric bioluminescent detection to allow sandwich immunoassays to be performed directly in solution.Yan NiBas J. H. M. RosierEva A. van AalenEva T. L. HanckmannLieuwe BiewengaAnna-Maria Makri PistikouBart TimmermansChris VuSophie RoosRemco ArtsWentao LiTom F. A. de GreefMarcel M. G. J. van BorrenFrank J. M. van KuppeveldBerend-Jan BoschMaarten MerkxNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yan Ni
Bas J. H. M. Rosier
Eva A. van Aalen
Eva T. L. Hanckmann
Lieuwe Biewenga
Anna-Maria Makri Pistikou
Bart Timmermans
Chris Vu
Sophie Roos
Remco Arts
Wentao Li
Tom F. A. de Greef
Marcel M. G. J. van Borren
Frank J. M. van Kuppeveld
Berend-Jan Bosch
Maarten Merkx
A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
description Many current immunoassays require multiple washing, incubation and optimization steps. Here the authors present Ratiometric Plug-and-Play Immunodiagnostics (RAPPID), a generic assay platform that uses ratiometric bioluminescent detection to allow sandwich immunoassays to be performed directly in solution.
format article
author Yan Ni
Bas J. H. M. Rosier
Eva A. van Aalen
Eva T. L. Hanckmann
Lieuwe Biewenga
Anna-Maria Makri Pistikou
Bart Timmermans
Chris Vu
Sophie Roos
Remco Arts
Wentao Li
Tom F. A. de Greef
Marcel M. G. J. van Borren
Frank J. M. van Kuppeveld
Berend-Jan Bosch
Maarten Merkx
author_facet Yan Ni
Bas J. H. M. Rosier
Eva A. van Aalen
Eva T. L. Hanckmann
Lieuwe Biewenga
Anna-Maria Makri Pistikou
Bart Timmermans
Chris Vu
Sophie Roos
Remco Arts
Wentao Li
Tom F. A. de Greef
Marcel M. G. J. van Borren
Frank J. M. van Kuppeveld
Berend-Jan Bosch
Maarten Merkx
author_sort Yan Ni
title A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
title_short A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
title_full A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
title_fullStr A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
title_full_unstemmed A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
title_sort plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9c6f00283d7b49f6a84e253e1ef16ce1
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