Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.

<h4>Objective</h4>Increasing evidence shows that TGF-β1 is a key mediator in diabetic nephropathy (DN) and induces renal fibrosis positively by Smad3 but negatively by Smad7. However, treatment of DN by blocking the TGF-β/Smad pathway remains limited. The present study investigated the a...

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Autores principales: Ting Ting Zhao, Hao Jun Zhang, Xiao Guang Lu, Xiao Ru Huang, Wei Ku Zhang, Hua Wang, Hui Yao Lan, Ping Li
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/9c734ae8c0d140e18335a1f5bb5242e1
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