Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation

Background: Lung cancer is the most common and lethal cancer around the world. Computed tomography (CT) is an integral imaging technique for staging the lung cancer. Aim of this study was to correlate the multidetector CT (MDCT) findings of lung nodule with histopathological examination, as well as...

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Autores principales:	Gupta Jagmohan, Gupta Parul, Gupta Suresh Chandra, Tak Amit
Formato:	article
Lenguaje:	EN SR
Publicado:	Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2021
Materias:	mdct fine needle aspiration cytology lung cancer sensitivity positive predictive value Medicine R
Acceso en línea:	https://doaj.org/article/9c7588e6a63d4a5ab90ebbea7d3c0eb9
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spelling	oai:doaj.org-article:9c7588e6a63d4a5ab90ebbea7d3c0eb92021-12-05T21:31:53ZOf multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation2490-33292303-795410.5937/scriptamed52-31903https://doaj.org/article/9c7588e6a63d4a5ab90ebbea7d3c0eb92021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2021/2490-33292103193G.pdfhttps://doaj.org/toc/2490-3329https://doaj.org/toc/2303-7954Background: Lung cancer is the most common and lethal cancer around the world. Computed tomography (CT) is an integral imaging technique for staging the lung cancer. Aim of this study was to correlate the multidetector CT (MDCT) findings of lung nodule with histopathological examination, as well as to assess the diagnostic accuracy of MDCT in evaluation of suspected lung nodule. Methods: One hundred patients with clinical or radiological suspicion of lung nodule referred for CT scan of thorax were included in the study. Histopathological analysis was performed. The location of the lesion was analysed and nodules were classified. Fine needle aspiration cytology (FNAC) was done with spinal needle under all aseptic precautions. The results obtained by MDCT were analysed and compared with histopathological findings done by CT guided FNAC. Results: Average age of patients was 65 years, 25 % were females and 75 % were males. Among all the patients 66 % of lesions were located in right side lung and 34 % of lesions were left in location. Of all, 2 % patients had lesions less than 3 cm, 11 % patients had lesion between 3-4 cm, 19 % patients had lesion between 4-5 cm, 26 % patients had lesion between 5-7 cm and 42 % patients had lesion greater than 7 cm. Many of these patients also presented with enlarged lymph nodes, most commonly mediastinal (73 %) followed by subcarinal (51 %), hilar (44 %) and supraclavicular (4 %) lymph nodes. The most common histological findings of lung nodules analysis were adenocarcinoma (41 %). Among the 100 patients 58 % had lesions located peripherally while 42 % had central lesions. CT was a highly sensitive (95.45 %) and moderately specific (75 %) test and also had a high positive predictive value (96 %) to diagnose malignant lung nodule. Conclusion: CT guided FNAC of lung nodule is a safe, minimal invasive procedure with a high diagnostic accuracy. The use of CT-guided FNAC in hilar and mediastinal nodules can avoid unnecessary exploratory surgery for staging and also diagnosis could be made with lesser cost.Gupta JagmohanGupta ParulGupta Suresh ChandraTak AmitMedical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicinearticlemdctfine needle aspiration cytologylung cancersensitivitypositive predictive valueMedicineRENSRScripta Medica, Vol 52, Iss 3, Pp 193-198 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	mdct fine needle aspiration cytology lung cancer sensitivity positive predictive value Medicine R
spellingShingle	mdct fine needle aspiration cytology lung cancer sensitivity positive predictive value Medicine R Gupta Jagmohan Gupta Parul Gupta Suresh Chandra Tak Amit Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
description	Background: Lung cancer is the most common and lethal cancer around the world. Computed tomography (CT) is an integral imaging technique for staging the lung cancer. Aim of this study was to correlate the multidetector CT (MDCT) findings of lung nodule with histopathological examination, as well as to assess the diagnostic accuracy of MDCT in evaluation of suspected lung nodule. Methods: One hundred patients with clinical or radiological suspicion of lung nodule referred for CT scan of thorax were included in the study. Histopathological analysis was performed. The location of the lesion was analysed and nodules were classified. Fine needle aspiration cytology (FNAC) was done with spinal needle under all aseptic precautions. The results obtained by MDCT were analysed and compared with histopathological findings done by CT guided FNAC. Results: Average age of patients was 65 years, 25 % were females and 75 % were males. Among all the patients 66 % of lesions were located in right side lung and 34 % of lesions were left in location. Of all, 2 % patients had lesions less than 3 cm, 11 % patients had lesion between 3-4 cm, 19 % patients had lesion between 4-5 cm, 26 % patients had lesion between 5-7 cm and 42 % patients had lesion greater than 7 cm. Many of these patients also presented with enlarged lymph nodes, most commonly mediastinal (73 %) followed by subcarinal (51 %), hilar (44 %) and supraclavicular (4 %) lymph nodes. The most common histological findings of lung nodules analysis were adenocarcinoma (41 %). Among the 100 patients 58 % had lesions located peripherally while 42 % had central lesions. CT was a highly sensitive (95.45 %) and moderately specific (75 %) test and also had a high positive predictive value (96 %) to diagnose malignant lung nodule. Conclusion: CT guided FNAC of lung nodule is a safe, minimal invasive procedure with a high diagnostic accuracy. The use of CT-guided FNAC in hilar and mediastinal nodules can avoid unnecessary exploratory surgery for staging and also diagnosis could be made with lesser cost.
format	article
author	Gupta Jagmohan Gupta Parul Gupta Suresh Chandra Tak Amit
author_facet	Gupta Jagmohan Gupta Parul Gupta Suresh Chandra Tak Amit
author_sort	Gupta Jagmohan
title	Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
title_short	Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
title_full	Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
title_fullStr	Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
title_full_unstemmed	Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation
title_sort	of multidetector computed tomography (mdct) in evaluation of lung nodule with histopathological correlation
publisher	Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
publishDate	2021
url	https://doaj.org/article/9c7588e6a63d4a5ab90ebbea7d3c0eb9
work_keys_str_mv	AT guptajagmohan ofmultidetectorcomputedtomographymdctinevaluationoflungnodulewithhistopathologicalcorrelation AT guptaparul ofmultidetectorcomputedtomographymdctinevaluationoflungnodulewithhistopathologicalcorrelation AT guptasureshchandra ofmultidetectorcomputedtomographymdctinevaluationoflungnodulewithhistopathologicalcorrelation AT takamit ofmultidetectorcomputedtomographymdctinevaluationoflungnodulewithhistopathologicalcorrelation
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Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation

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