Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography

Ilias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual d...

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Autores principales: Georgalas I, Paraskevopoulos T, Papaconstantinou D, Brouzas D, Koutsandrea C
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Publicado: Dove Medical Press 2013
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Acceso en línea:https://doaj.org/article/9c7b122e821e4f94bef1b4dd842aedd4
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spelling oai:doaj.org-article:9c7b122e821e4f94bef1b4dd842aedd42021-12-02T00:28:16ZLarge bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography1177-54671177-5483https://doaj.org/article/9c7b122e821e4f94bef1b4dd842aedd42013-04-01T00:00:00Zhttp://www.dovepress.com/large-bilateral-foveal-cysts-in-the-inner-retina-of-a-patient-treated--a12714https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ilias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. Method: Observational case report. Results: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. Conclusion: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient's vision and subsequently their quality of life. Keywords: maculopathy, OCTGeorgalas IParaskevopoulos TPapaconstantinou DBrouzas DKoutsandrea CDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 707-709 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
description Ilias Georgalas, Theodore Paraskevopoulos, Dimitris Papaconstaninou, Dimitiris Brouzas, Chryssanthi Koutsandrea Department of Ophthalmology, "G Gennimatas" Hospital of Athens, NHS, University of Athens, Athens, Greece Purpose: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. Method: Observational case report. Results: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. Conclusion: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient's vision and subsequently their quality of life. Keywords: maculopathy, OCT
format article
author Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
author_facet Georgalas I
Paraskevopoulos T
Papaconstantinou D
Brouzas D
Koutsandrea C
author_sort Georgalas I
title Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_short Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_full Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_fullStr Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_full_unstemmed Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
title_sort large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with fourier-domain optical coherence tomography
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/9c7b122e821e4f94bef1b4dd842aedd4
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