Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations

The prevalence of genotypes and alleles of polymorphic markers (-75)G>A and (+83)C>T apolipoprotein A1 gene (ApOAl) in samples of ethnic groups from Eastern Siberia (the Evenkis and Buryats) were studied. In the Evenki population allele (-75)A was registered in 22,7 % cases, in the Buryat popu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	S. I. Kolesnikov, T. A. Bairova, O. V. Kalyuzhnaya, A. A. Trukhin, O. A. Ershova, M. A. Darenskaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	apolipoprotein lipids gene Science Q
Acceso en línea:	https://doaj.org/article/9c7d11e0d51749b49361b6b0e435dd10
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9c7d11e0d51749b49361b6b0e435dd10
record_format	dspace
spelling	oai:doaj.org-article:9c7d11e0d51749b49361b6b0e435dd102021-11-23T06:14:32ZPolymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations2541-94202587-9596https://doaj.org/article/9c7d11e0d51749b49361b6b0e435dd102015-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/75https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The prevalence of genotypes and alleles of polymorphic markers (-75)G>A and (+83)C>T apolipoprotein A1 gene (ApOAl) in samples of ethnic groups from Eastern Siberia (the Evenkis and Buryats) were studied. In the Evenki population allele (-75)A was registered in 22,7 % cases, in the Buryat population - in 22,4 % cases. In the Evenki population allele (+83)T was found in 6,3 % cases, in the Buryat population - in 5,9 % cases. Statistically significant differences of genotypes and alleles APOA1 prevalence between the Evenkis and the Buryats was not found. The prevalence of alleles (-75)G>A and (+83)C>T of gene APOA1 obtained in the study were compared with the prevalence in different populations around the world. For each teenager in the study group we conducted a biochemical analysis of serum lipid profile. Also a comparative analysis of blood lipid profile in carriers of different genotypes was carried out. Comparative analysis of blood lipid profile in carriers of different genotypes was conducted.S. I. KolesnikovT. A. BairovaO. V. KalyuzhnayaA. A. TrukhinO. A. ErshovaM. A. DarenskayaScientific Сentre for Family Health and Human Reproduction ProblemsarticleapolipoproteinlipidsgeneScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3, Pp 74-78 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	apolipoprotein lipids gene Science Q
spellingShingle	apolipoprotein lipids gene Science Q S. I. Kolesnikov T. A. Bairova O. V. Kalyuzhnaya A. A. Trukhin O. A. Ershova M. A. Darenskaya Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
description	The prevalence of genotypes and alleles of polymorphic markers (-75)G>A and (+83)C>T apolipoprotein A1 gene (ApOAl) in samples of ethnic groups from Eastern Siberia (the Evenkis and Buryats) were studied. In the Evenki population allele (-75)A was registered in 22,7 % cases, in the Buryat population - in 22,4 % cases. In the Evenki population allele (+83)T was found in 6,3 % cases, in the Buryat population - in 5,9 % cases. Statistically significant differences of genotypes and alleles APOA1 prevalence between the Evenkis and the Buryats was not found. The prevalence of alleles (-75)G>A and (+83)C>T of gene APOA1 obtained in the study were compared with the prevalence in different populations around the world. For each teenager in the study group we conducted a biochemical analysis of serum lipid profile. Also a comparative analysis of blood lipid profile in carriers of different genotypes was carried out. Comparative analysis of blood lipid profile in carriers of different genotypes was conducted.
format	article
author	S. I. Kolesnikov T. A. Bairova O. V. Kalyuzhnaya A. A. Trukhin O. A. Ershova M. A. Darenskaya
author_facet	S. I. Kolesnikov T. A. Bairova O. V. Kalyuzhnaya A. A. Trukhin O. A. Ershova M. A. Darenskaya
author_sort	S. I. Kolesnikov
title	Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
title_short	Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
title_full	Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
title_fullStr	Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
title_full_unstemmed	Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations
title_sort	polymorphism of apolipoprotein a1 gene and lipid profile of blood serum in the evenki and buryat populations
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/9c7d11e0d51749b49361b6b0e435dd10
work_keys_str_mv	AT sikolesnikov polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations AT tabairova polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations AT ovkalyuzhnaya polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations AT aatrukhin polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations AT oaershova polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations AT madarenskaya polymorphismofapolipoproteina1geneandlipidprofileofbloodserumintheevenkiandburyatpopulations
_version_	1718417085893181440

Polymorphism of apolipoprotein A1 gene and lipid profile of blood serum in the Evenki and Buryat populations

Ejemplares similares