Structural visualization of transcription activated by a multidrug-sensing MerR family regulator

The MerR family of transcriptional regulators, such as EcmrR, activate promoters with a structure that is suboptimal for recognition by RNA polymerase holoenzyme. Structural insights into the EcmrR-dependent transcription process elucidate the mechanisms enabling optimal promoter recognition and tra...

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Autores principales:	Yang Yang, Chang Liu, Wei Zhou, Wei Shi, Ming Chen, Baoyue Zhang, David G. Schatz, Yangbo Hu, Bin Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9c818f9780e14597af4ed38220cb42d1
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spelling	oai:doaj.org-article:9c818f9780e14597af4ed38220cb42d12021-12-02T14:35:33ZStructural visualization of transcription activated by a multidrug-sensing MerR family regulator10.1038/s41467-021-22990-82041-1723https://doaj.org/article/9c818f9780e14597af4ed38220cb42d12021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22990-8https://doaj.org/toc/2041-1723The MerR family of transcriptional regulators, such as EcmrR, activate promoters with a structure that is suboptimal for recognition by RNA polymerase holoenzyme. Structural insights into the EcmrR-dependent transcription process elucidate the mechanisms enabling optimal promoter recognition and transition from initiation to elongation.Yang YangChang LiuWei ZhouWei ShiMing ChenBaoyue ZhangDavid G. SchatzYangbo HuBin LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yang Yang Chang Liu Wei Zhou Wei Shi Ming Chen Baoyue Zhang David G. Schatz Yangbo Hu Bin Liu Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
description	The MerR family of transcriptional regulators, such as EcmrR, activate promoters with a structure that is suboptimal for recognition by RNA polymerase holoenzyme. Structural insights into the EcmrR-dependent transcription process elucidate the mechanisms enabling optimal promoter recognition and transition from initiation to elongation.
format	article
author	Yang Yang Chang Liu Wei Zhou Wei Shi Ming Chen Baoyue Zhang David G. Schatz Yangbo Hu Bin Liu
author_facet	Yang Yang Chang Liu Wei Zhou Wei Shi Ming Chen Baoyue Zhang David G. Schatz Yangbo Hu Bin Liu
author_sort	Yang Yang
title	Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
title_short	Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
title_full	Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
title_fullStr	Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
title_full_unstemmed	Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
title_sort	structural visualization of transcription activated by a multidrug-sensing merr family regulator
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9c818f9780e14597af4ed38220cb42d1
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Structural visualization of transcription activated by a multidrug-sensing MerR family regulator

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