β5 integrin up-regulation in brain-derived neurotrophic factor promotes cell motility in human chondrosarcoma.

Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs. Brain derived neurotrophic factor (BDNF) is a small-molecule protein from the neurotrophin family of...

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Main Authors: Chih-Yang Lin, Hui-Jye Chen, Te-Mao Li, Yi-Chin Fong, Shan-Chi Liu, Po-Chun Chen, Chih-Hsin Tang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/9c836448b2aa4ed9bb452ac5ef42a01e
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