Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells
Abstract Mitochondria receive cholesterol from late endosomes and lysosomes (LE/LYSs) or from the plasma membrane for production of oxysterols and steroid hormones. This process depends on the endo-lysosomal sterol transfer protein Niemann Pick C2 (NPC2). Using the intrinsically fluorescent choleste...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/9c8c613b5a6d43229d449d238c083ed0 |
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