Conventional and novel stem cell based therapies for androgenic alopecia

Dodanim Talavera-Adame,1 Daniella Newman,2 Nathan Newman1 1American Advanced Medical Corp. (Private Practice), Beverly Hills, CA, 2Western University of Health Sciences, Pomona, CA, USA Abstract: The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patien...

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Autores principales: Talavera-Adame D, Newman D, Newman N
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Lenguaje:EN
Publicado: Dove Medical Press 2017
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spelling oai:doaj.org-article:9c92ac0ff2b445a29a5f3fe0971514f12021-12-02T03:14:09ZConventional and novel stem cell based therapies for androgenic alopecia1178-6957https://doaj.org/article/9c92ac0ff2b445a29a5f3fe0971514f12017-08-01T00:00:00Zhttps://www.dovepress.com/conventional-and-novel-stem-cell-based-therapies-for-androgenic-alopec-peer-reviewed-article-SCCAAhttps://doaj.org/toc/1178-6957Dodanim Talavera-Adame,1 Daniella Newman,2 Nathan Newman1 1American Advanced Medical Corp. (Private Practice), Beverly Hills, CA, 2Western University of Health Sciences, Pomona, CA, USA Abstract: The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patients diagnosed with AGA may experience decreased quality of life, depression, and feel self-conscious. There are a variety of therapeutic options ranging from prescription drugs to non-prescription medications. Currently, AGA involves an annual global market revenue of US$4 billion and a growth rate of 1.8%, indicating a growing consumer market. Although natural and synthetic ingredients can promote hair growth and, therefore, be useful to treat AGA, some of them have important adverse effects and unknown mechanisms of action that limit their use and benefits. Biologic factors that include signaling from stem cells, dermal papilla cells, and platelet-rich plasma are some of the current therapeutic agents being studied for hair restoration with milder side effects. However, most of the mechanisms exerted by these factors in hair restoration are still being researched. In this review, we analyze the therapeutic agents that have been used for AGA and emphasize the potential of new therapies based on advances in stem cell technologies and regenerative medicine. Keywords: stem cells, stem cell therapies, hair follicle, dermal papilla, androgenic alopecia, laser, hair regenerationTalavera-Adame DNewman DNewman NDove Medical Pressarticlestem cell therapyhair follicledermal papilla cellsandrogenic alopeciahair growthlaser therapyCytologyQH573-671ENStem Cells and Cloning: Advances and Applications, Vol Volume 10, Pp 11-19 (2017)
institution DOAJ
collection DOAJ
language EN
topic stem cell therapy
hair follicle
dermal papilla cells
androgenic alopecia
hair growth
laser therapy
Cytology
QH573-671
spellingShingle stem cell therapy
hair follicle
dermal papilla cells
androgenic alopecia
hair growth
laser therapy
Cytology
QH573-671
Talavera-Adame D
Newman D
Newman N
Conventional and novel stem cell based therapies for androgenic alopecia
description Dodanim Talavera-Adame,1 Daniella Newman,2 Nathan Newman1 1American Advanced Medical Corp. (Private Practice), Beverly Hills, CA, 2Western University of Health Sciences, Pomona, CA, USA Abstract: The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patients diagnosed with AGA may experience decreased quality of life, depression, and feel self-conscious. There are a variety of therapeutic options ranging from prescription drugs to non-prescription medications. Currently, AGA involves an annual global market revenue of US$4 billion and a growth rate of 1.8%, indicating a growing consumer market. Although natural and synthetic ingredients can promote hair growth and, therefore, be useful to treat AGA, some of them have important adverse effects and unknown mechanisms of action that limit their use and benefits. Biologic factors that include signaling from stem cells, dermal papilla cells, and platelet-rich plasma are some of the current therapeutic agents being studied for hair restoration with milder side effects. However, most of the mechanisms exerted by these factors in hair restoration are still being researched. In this review, we analyze the therapeutic agents that have been used for AGA and emphasize the potential of new therapies based on advances in stem cell technologies and regenerative medicine. Keywords: stem cells, stem cell therapies, hair follicle, dermal papilla, androgenic alopecia, laser, hair regeneration
format article
author Talavera-Adame D
Newman D
Newman N
author_facet Talavera-Adame D
Newman D
Newman N
author_sort Talavera-Adame D
title Conventional and novel stem cell based therapies for androgenic alopecia
title_short Conventional and novel stem cell based therapies for androgenic alopecia
title_full Conventional and novel stem cell based therapies for androgenic alopecia
title_fullStr Conventional and novel stem cell based therapies for androgenic alopecia
title_full_unstemmed Conventional and novel stem cell based therapies for androgenic alopecia
title_sort conventional and novel stem cell based therapies for androgenic alopecia
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/9c92ac0ff2b445a29a5f3fe0971514f1
work_keys_str_mv AT talaveraadamed conventionalandnovelstemcellbasedtherapiesforandrogenicalopecia
AT newmand conventionalandnovelstemcellbasedtherapiesforandrogenicalopecia
AT newmann conventionalandnovelstemcellbasedtherapiesforandrogenicalopecia
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