Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

Abstract The immature phenotype of human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) constrains their potential in cell therapy and drug testing. In this study, we report that shifting hPSC-CMs from glucose-containing to galactose- and fatty acid-containing medium promotes their fast mat...

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Autores principales: Cláudia Correia, Alexey Koshkin, Patrícia Duarte, Dongjian Hu, Ana Teixeira, Ibrahim Domian, Margarida Serra, Paula M. Alves
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/9c935c36e30c479f9006244f67d812d0
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