Design, synthesis of new novel quinoxalin-2(1H)-one derivatives incorporating hydrazone, hydrazine, and pyrazole moieties as antimicrobial potential with in-silico ADME and molecular docking simulation
A series of 6-(morpholinosulfonyl)quinoxalin-2(1H)-one based hydrazone, hydrazine, and pyrazole moieties were designed, synthesized, and evaluated for their in vitro antimicrobial activity. All the synthesized quinoxaline derivatives were characterized by IR, NMR (1H /13C), and EI MS. The results di...
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Autores principales: | Ahmed Ragab, Doaa M. Elsisi, Ola A. Abu Ali, Moustafa S. Abusaif, Ahmed A. Askar, Awatef A. Farag, Yousry A. Ammar |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/9c96fd9f9736450982119d8ffe59f359 |
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