Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages

ABSTRACT The scavenger receptor MARCO is expressed in several subsets of naive tissue-resident macrophages and has been shown to participate in the recognition of various bacterial pathogens. However, the role of MARCO in antiviral defense is largely unexplored. Here, we investigated whether MARCO m...

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Auteurs principaux: Mareike D. Maler, Peter J. Nielsen, Nicole Stichling, Idan Cohen, Zsolt Ruzsics, Connor Wood, Peggy Engelhard, Maarit Suomalainen, Ildiko Gyory, Michael Huber, Joachim Müller-Quernheim, Wolfgang W. A. Schamel, Siamon Gordon, Thilo Jakob, Stefan F. Martin, Willi Jahnen-Dechent, Urs F. Greber, Marina A. Freudenberg, György Fejer
Format: article
Langue:EN
Publié: American Society for Microbiology 2017
Sujets:
IL-1α
MARCO
MPI cells
adenovirus
cGAS
cytokines
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/9c98ffb98e534f1895fead53be5d0402
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