Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody

Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody

The tick-borne encephalitis virus (TBEV) causes thousands of cases of meningitis and encephalitis annually. Here, the authors describe a cryo-EM structure of the TBEV virion bound by Fab fragments of the neutralizing antibody 19/1786, revealing a mechanism whereby this antibody prevents virus membra...

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Autores principales: Tibor Füzik, Petra Formanová, Daniel Růžek, Kentaro Yoshii, Matthias Niedrig, Pavel Plevka
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/9ca299bbfe594c17985845abd4f92848
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