Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors

How the Mycoplasma genitalium cytadhesins P140 and P110 promote host cell invasion remains poorly understood. Here, combining structural analysis with functional assays, Aparicio et al. identify the P110 domain that binds to sialylated receptors essential for mycoplasma cytadherence.

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Autores principales:	David Aparicio, Sergi Torres-Puig, Mercè Ratera, Enrique Querol, Jaume Piñol, Oscar Q. Pich, Ignacio Fita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9cb10b9b3ad9431bbf28f1f147614855
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spelling	oai:doaj.org-article:9cb10b9b3ad9431bbf28f1f1476148552021-12-02T16:49:19ZMycoplasma genitalium adhesin P110 binds sialic-acid human receptors10.1038/s41467-018-06963-y2041-1723https://doaj.org/article/9cb10b9b3ad9431bbf28f1f1476148552018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06963-yhttps://doaj.org/toc/2041-1723How the Mycoplasma genitalium cytadhesins P140 and P110 promote host cell invasion remains poorly understood. Here, combining structural analysis with functional assays, Aparicio et al. identify the P110 domain that binds to sialylated receptors essential for mycoplasma cytadherence.David AparicioSergi Torres-PuigMercè RateraEnrique QuerolJaume PiñolOscar Q. PichIgnacio FitaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David Aparicio Sergi Torres-Puig Mercè Ratera Enrique Querol Jaume Piñol Oscar Q. Pich Ignacio Fita Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
description	How the Mycoplasma genitalium cytadhesins P140 and P110 promote host cell invasion remains poorly understood. Here, combining structural analysis with functional assays, Aparicio et al. identify the P110 domain that binds to sialylated receptors essential for mycoplasma cytadherence.
format	article
author	David Aparicio Sergi Torres-Puig Mercè Ratera Enrique Querol Jaume Piñol Oscar Q. Pich Ignacio Fita
author_facet	David Aparicio Sergi Torres-Puig Mercè Ratera Enrique Querol Jaume Piñol Oscar Q. Pich Ignacio Fita
author_sort	David Aparicio
title	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
title_short	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
title_full	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
title_fullStr	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
title_full_unstemmed	Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors
title_sort	mycoplasma genitalium adhesin p110 binds sialic-acid human receptors
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9cb10b9b3ad9431bbf28f1f147614855
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Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors

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