Natural hypothalamic circuit dynamics underlying object memorization

Hypothalamus is implicated in memory disorders but the neural mechanisms are unknown. Here, the authors report that MCH expressing hypothalamic neurons respond to novel object exposure, are inhibited by local GAD65 expressing neurons and these local circuit interactions are causally involved in obje...

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Detalles Bibliográficos
Autores principales:	Christin Kosse, Denis Burdakov
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9cb8c0058d13439080b6efe8a4730ed3
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spelling	oai:doaj.org-article:9cb8c0058d13439080b6efe8a4730ed32021-12-02T14:40:20ZNatural hypothalamic circuit dynamics underlying object memorization10.1038/s41467-019-10484-72041-1723https://doaj.org/article/9cb8c0058d13439080b6efe8a4730ed32019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10484-7https://doaj.org/toc/2041-1723Hypothalamus is implicated in memory disorders but the neural mechanisms are unknown. Here, the authors report that MCH expressing hypothalamic neurons respond to novel object exposure, are inhibited by local GAD65 expressing neurons and these local circuit interactions are causally involved in object memory formation.Christin KosseDenis BurdakovNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christin Kosse Denis Burdakov Natural hypothalamic circuit dynamics underlying object memorization
description	Hypothalamus is implicated in memory disorders but the neural mechanisms are unknown. Here, the authors report that MCH expressing hypothalamic neurons respond to novel object exposure, are inhibited by local GAD65 expressing neurons and these local circuit interactions are causally involved in object memory formation.
format	article
author	Christin Kosse Denis Burdakov
author_facet	Christin Kosse Denis Burdakov
author_sort	Christin Kosse
title	Natural hypothalamic circuit dynamics underlying object memorization
title_short	Natural hypothalamic circuit dynamics underlying object memorization
title_full	Natural hypothalamic circuit dynamics underlying object memorization
title_fullStr	Natural hypothalamic circuit dynamics underlying object memorization
title_full_unstemmed	Natural hypothalamic circuit dynamics underlying object memorization
title_sort	natural hypothalamic circuit dynamics underlying object memorization
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9cb8c0058d13439080b6efe8a4730ed3
work_keys_str_mv	AT christinkosse naturalhypothalamiccircuitdynamicsunderlyingobjectmemorization AT denisburdakov naturalhypothalamiccircuitdynamicsunderlyingobjectmemorization
_version_	1718390313834250240

Natural hypothalamic circuit dynamics underlying object memorization

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