Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro

Cellular cargo transported along actin filaments is faced with a directional choice at an intersection. Here the authors show that myosin Va-bound cargo prefers to go straight through the intersection, and propose a model to explain this by a tug-of-war between motors on the lipid cargo that engage...

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Autores principales:	Andrew T. Lombardo, Shane R. Nelson, M. Yusuf Ali, Guy G. Kennedy, Kathleen M. Trybus, Sam Walcott, David M. Warshaw
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9cbbb6d752f74a68bb343e25f12b6f66
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spelling	oai:doaj.org-article:9cbbb6d752f74a68bb343e25f12b6f662021-12-02T14:42:40ZMyosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro10.1038/ncomms156922041-1723https://doaj.org/article/9cbbb6d752f74a68bb343e25f12b6f662017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15692https://doaj.org/toc/2041-1723Cellular cargo transported along actin filaments is faced with a directional choice at an intersection. Here the authors show that myosin Va-bound cargo prefers to go straight through the intersection, and propose a model to explain this by a tug-of-war between motors on the lipid cargo that engage the actin tracks.Andrew T. LombardoShane R. NelsonM. Yusuf AliGuy G. KennedyKathleen M. TrybusSam WalcottDavid M. WarshawNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrew T. Lombardo Shane R. Nelson M. Yusuf Ali Guy G. Kennedy Kathleen M. Trybus Sam Walcott David M. Warshaw Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
description	Cellular cargo transported along actin filaments is faced with a directional choice at an intersection. Here the authors show that myosin Va-bound cargo prefers to go straight through the intersection, and propose a model to explain this by a tug-of-war between motors on the lipid cargo that engage the actin tracks.
format	article
author	Andrew T. Lombardo Shane R. Nelson M. Yusuf Ali Guy G. Kennedy Kathleen M. Trybus Sam Walcott David M. Warshaw
author_facet	Andrew T. Lombardo Shane R. Nelson M. Yusuf Ali Guy G. Kennedy Kathleen M. Trybus Sam Walcott David M. Warshaw
author_sort	Andrew T. Lombardo
title	Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
title_short	Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
title_full	Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
title_fullStr	Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
title_full_unstemmed	Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
title_sort	myosin va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9cbbb6d752f74a68bb343e25f12b6f66
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Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro

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