A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial cells are separated by an extracellular matrix...

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Autores principales:	Astgik Petrosyan, Paolo Cravedi, Valentina Villani, Andrea Angeletti, Joaquin Manrique, Alessandra Renieri, Roger E. De Filippo, Laura Perin, Stefano Da Sacco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9cbdce13fe804916beea7bf8ae1c1d49
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spelling	oai:doaj.org-article:9cbdce13fe804916beea7bf8ae1c1d492021-12-02T14:39:40ZA glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier10.1038/s41467-019-11577-z2041-1723https://doaj.org/article/9cbdce13fe804916beea7bf8ae1c1d492019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11577-zhttps://doaj.org/toc/2041-1723The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial cells are separated by an extracellular matrix resembling the in vivo basement membrane.Astgik PetrosyanPaolo CravediValentina VillaniAndrea AngelettiJoaquin ManriqueAlessandra RenieriRoger E. De FilippoLaura PerinStefano Da SaccoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Astgik Petrosyan Paolo Cravedi Valentina Villani Andrea Angeletti Joaquin Manrique Alessandra Renieri Roger E. De Filippo Laura Perin Stefano Da Sacco A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
description	The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial cells are separated by an extracellular matrix resembling the in vivo basement membrane.
format	article
author	Astgik Petrosyan Paolo Cravedi Valentina Villani Andrea Angeletti Joaquin Manrique Alessandra Renieri Roger E. De Filippo Laura Perin Stefano Da Sacco
author_facet	Astgik Petrosyan Paolo Cravedi Valentina Villani Andrea Angeletti Joaquin Manrique Alessandra Renieri Roger E. De Filippo Laura Perin Stefano Da Sacco
author_sort	Astgik Petrosyan
title	A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
title_short	A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
title_full	A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
title_fullStr	A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
title_full_unstemmed	A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
title_sort	glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9cbdce13fe804916beea7bf8ae1c1d49
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A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

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