Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint

Osteochondritis dissecans (OCD) is a chronic and painful joint condition that can occur from childhood through to adult life. Microtrauma, vascular insufficiency, or abnormal endochondral ossification are the most common causes of OCD. Reconstructive techniques for OCD of the knee are typically nece...

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Autores principales:	Tommaso Roberti Di Sarsisa, Michele Fiore, Vito Coco, Marco Govoni, Leonardo Vivarelli, Nicola Rani, Nicolandrea Del Piccolo, Dante Dallari
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	osteochondral allograft transplantation osteochondritis dissecans knee lesion healing Science Q
Acceso en línea:	https://doaj.org/article/9cbf8261307940e1afc6555a9cd35264
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spelling	oai:doaj.org-article:9cbf8261307940e1afc6555a9cd352642021-11-25T18:11:10ZFresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint10.3390/life111112052075-1729https://doaj.org/article/9cbf8261307940e1afc6555a9cd352642021-11-01T00:00:00Zhttps://www.mdpi.com/2075-1729/11/11/1205https://doaj.org/toc/2075-1729Osteochondritis dissecans (OCD) is a chronic and painful joint condition that can occur from childhood through to adult life. Microtrauma, vascular insufficiency, or abnormal endochondral ossification are the most common causes of OCD. Reconstructive techniques for OCD of the knee are typically necessary when either non-operative or reparative/regenerative operative treatments fail, or when the OCD is irreversible. To analyze the clinical outcomes and failure rates of fresh osteochondral allograft transplantation (FOCA) used as a reconstructive strategy in OCD patients, an in-depth search was carried out on the PubMed, Scopus, and Web of Science databases concerning the existing evidence related to the use of FOCA for OCD patients in the knee joint. A total of 646 studies were found through the search and 2 studies were added after a cross-referenced examination of the articles within the bibliography. Six studies with a total of 303 OCD lesions treated with FOCA, with a mean follow-up of 6.3 years, were included. Although a limited number of low-level evidence studies on this topic are available in previous research, satisfactory clinical results and survival rates of the reconstruction are reported. However, to better define the real advantages of FOCA in the healing process of OCD lesions, comparative studies with different techniques are needed.Tommaso Roberti Di SarsisaMichele FioreVito CocoMarco GovoniLeonardo VivarelliNicola RaniNicolandrea Del PiccoloDante DallariMDPI AGarticleosteochondral allograft transplantationosteochondritis dissecanskneelesionhealingScienceQENLife, Vol 11, Iss 1205, p 1205 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	osteochondral allograft transplantation osteochondritis dissecans knee lesion healing Science Q
spellingShingle	osteochondral allograft transplantation osteochondritis dissecans knee lesion healing Science Q Tommaso Roberti Di Sarsisa Michele Fiore Vito Coco Marco Govoni Leonardo Vivarelli Nicola Rani Nicolandrea Del Piccolo Dante Dallari Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
description	Osteochondritis dissecans (OCD) is a chronic and painful joint condition that can occur from childhood through to adult life. Microtrauma, vascular insufficiency, or abnormal endochondral ossification are the most common causes of OCD. Reconstructive techniques for OCD of the knee are typically necessary when either non-operative or reparative/regenerative operative treatments fail, or when the OCD is irreversible. To analyze the clinical outcomes and failure rates of fresh osteochondral allograft transplantation (FOCA) used as a reconstructive strategy in OCD patients, an in-depth search was carried out on the PubMed, Scopus, and Web of Science databases concerning the existing evidence related to the use of FOCA for OCD patients in the knee joint. A total of 646 studies were found through the search and 2 studies were added after a cross-referenced examination of the articles within the bibliography. Six studies with a total of 303 OCD lesions treated with FOCA, with a mean follow-up of 6.3 years, were included. Although a limited number of low-level evidence studies on this topic are available in previous research, satisfactory clinical results and survival rates of the reconstruction are reported. However, to better define the real advantages of FOCA in the healing process of OCD lesions, comparative studies with different techniques are needed.
format	article
author	Tommaso Roberti Di Sarsisa Michele Fiore Vito Coco Marco Govoni Leonardo Vivarelli Nicola Rani Nicolandrea Del Piccolo Dante Dallari
author_facet	Tommaso Roberti Di Sarsisa Michele Fiore Vito Coco Marco Govoni Leonardo Vivarelli Nicola Rani Nicolandrea Del Piccolo Dante Dallari
author_sort	Tommaso Roberti Di Sarsisa
title	Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
title_short	Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
title_full	Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
title_fullStr	Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
title_full_unstemmed	Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint
title_sort	fresh osteochondral allograft transplantation in osteochondritis dissecans in the knee joint
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9cbf8261307940e1afc6555a9cd35264
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Fresh Osteochondral Allograft Transplantation in Osteochondritis Dissecans in the Knee Joint

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