A competitive ligand-binding assay for the detection of neutralizing antibodies against dostarlimab (TSR-042)
Abstract Dostarlimab is a humanized anti–PD-1 monoclonal antibody. Dostarlimab (JEMPERLI; TSR-042) was recently approved in the USA and in the EU. The presence of neutralizing antibodies (NAbs) is a cause for concern because they block the therapeutic function of the antibody and reduce drug efficac...
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Main Authors: | Xiaolong Tom Zhang, Hong Chen, Weiping Shao, Zhongping John Lin, Murad Melhem, Sharon Lu |
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Format: | article |
Language: | EN |
Published: |
SpringerOpen
2021
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Subjects: | |
Online Access: | https://doaj.org/article/9cc562b825a24dee8a7fce5d389aa00c |
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