mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses
ABSTRACT Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus, with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how “Sub-Telomere Directed Gene Expression during Initi...
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2019
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Acceso en línea: | https://doaj.org/article/9cccd22660e64d0e8de7bfdc42bb2c47 |
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Sumario: | ABSTRACT Jorge Amich studies several aspects of sulfur and nitrogen metabolism in Aspergillus fumigatus, with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how “Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis” (A. McDonagh, N. D. Fedorova, J. Crabtree, Y. Yu, S. Kim, et al., PLoS Pathog 4:e1000154, 2008, https://doi.org/10.1371/journal.ppat.1000154) impacted his thinking about in vivo metabolism and how to investigate it. |
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